Genetics of Streptomyces rimosus , the Oxytetracycline Producer
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چکیده
منابع مشابه
Genetics of Streptomyces rimosus, the oxytetracycline producer.
From a genetic standpoint, Streptomyces rimosus is arguably the best-characterized industrial streptomycete as the producer of oxytetracycline and other tetracycline antibiotics. Although resistance to these antibiotics has reduced their clinical use in recent years, tetracyclines have an increasing role in the treatment of emerging infections and noninfective diseases. Procedures for in vivo a...
متن کاملPRODUCTION OF OXYTETRACYCLINE BY ISOLATED WILD TYPE IRANIAN STREPTOMYCES RIMOSUS
Production of oxytetracycline by an isolated strain of Streptomyces rimosus from Iranian soil was investigated using a special fermentation medium. A comparative study was performed with standard strain PTCC 1144 using the following parameters optimum growth conditions with respect to time, pH, and different amounts of corn steep liquor. Surprisingly, the production yield of the wild strai...
متن کاملInfluence of Inorganic Phosphorus on Oxytetracycline Formation by Streptomyces Rimosus.
Production of oxytetracycline by Streptomyces rimosus in several chemically defined media containing graded concentrations of inorganic phosphorus was studied in shake flasks. Although high levels of inorganic phosphate have been reported to inhibit oxytetracycline formation, this study indicated that composition of the medium is an important factor in determining whether antibiotic production ...
متن کاملOxytetracycline Formation by Streptomyces rimosus in Chemically Defined Media.
Details in the fermentation of oxytetracycline in a synthetic medium with Streptomyces rimosus have been presented. In these studies, an organic nitrogen source was shown to be essential for the production of significant amounts of antibiotic activity. Of the amino acids tested, aspartic acid, proline, threonine, valine, and beta-alanine were utilized well for both growth and antibiotic product...
متن کاملproduction of oxytetracycline by isolated wild type iranian streptomyces rimosus
production of oxytetracycline by an isolated strain of streptomyces rimosus from iranian soil was investigated using a special fermentation medium. a comparative study was performed with standard strain ptcc 1144 using the following parameters optimum growth conditions with respect to time, ph, and different amounts of corn steep liquor. surprisingly, the production yield of the wild strain was...
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ژورنال
عنوان ژورنال: Microbiology and Molecular Biology Reviews
سال: 2006
ISSN: 1092-2172,1098-5557
DOI: 10.1128/mmbr.00004-06